2022 MLB odds, picks, predictions for Wednesday, May 18 from proven model: This four-way parlay pays 15-1

Shohei Ohtani and the Los Angeles Angels take on the Texas Rangers on Wednesday at 8:05 p.m. ET. The game is one of 15 on MLB's schedule on that day. SportsLine's prediction model simulates every MLB game 10,000 times and is on a 33-25 roll on top-rated MLB money-line picks through six weeks. It has returned over $300 for $100 players.

The model simulates every game on Wednesday's schedule 10,000 times. It is high on the Cleveland Guardians to beat the Cincinnati Reds at 6:10 p.m. ET. The Guardians have dominated their interstate rivals recently, winning four of the last five meetings between the teams. Tyler Mahle has struggled this season, but he is 0-2 with a 6.61 ERA in his career against Cleveland.

The model has selected a four-way parlay with a payout of 15-1 for Wednesday. It also has a play that wins outright over 50 percent of the time.