Celtics vs. Timberwolves odds, line, spread: 2022 NBA picks, March 27 prediction from proven computer model

Celtics are 25-12 at home and have won 12 of their last 14 games since the All-Star break. Minnesota is 43-32 overall and 4-2 on the road since break, while Boston is favored by six points. The Timberwolves won the last meeting 108-103 on December 27. SportsLine's advanced computer model simulates every NBA game 10,000 times and has returned well over $10,00 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons.

SportsLine's computer model has set its sights on Celtics vs. Timberwolves. The model is backing Celtics.

Boston Celtics beat Utah Jazz 125-97 on Wednesday. Jayson Tatum and Jaylen Brown were the main playmakers for Boston. The Celtics are on a five-game winning streak. Boston has held its opponents to 103.8 points per game this season.

Karl-Anthony Towns and Jordan McLaughlin had a good game against Dallas Mavericks. Towns has been the Timberwolves' most efficient shooter from beyond the arc this season at 40.9 percent. Boston has had the best 3-point defense in the league this year, but has allowed opponents to hit 34.8 percent of their shots over their last three games.

The model simulates Celtics vs. Timberwolves 10,000 times and it's picking Celtics. The model is leaning towards the Celtics, but it also has a point-spread pick that hits in almost 60 percent of simulations.