College Football Odds: Louisville-UCF prediction, odds and pick

Louisville is coming off a 31-7 drubbing at the hands of Syracuse in their season opener. The loss may have started the clock on the end of head coach Scott Satterfield's time with the program.

Louisville's quarterback Malik Cunningham is in his fifth season with the program. He has played in 47 games so far and has tossed 62 touchdowns and just 26 interceptions. The team's running game is bolstered by Cunningham, who ran for 20 touchdowns last season. Tiyon Evans, a transfer from Tennessee, is the main ball carrier and ran 89 yards and the team’s lone touchdown. Senior receiver Tyler Hudson caught eight passes for 102 yards in the opener. Benjamin Perry led the group with eight tackles for a loss.

John Rhys Plumlee is the new starting quarterback for UCF. He was 20-31 for 308 yards and four touchdowns in the opener. The defense dominated an inferior opponent in week one. Louisville is a lot different than trying to stop South Carolina State.

Louisville and UCF are playing a quarterback matchup.

Louisville is favored by 5.5 points over UCF.