Cotton Bowl Odds: Notre Dame vs. Clemson Betting Preview, Pick

Clemson and Notre Dame are playing in the Cotton Bowl. Clemson is 12-6 both straight up and against the spread in postseason games under coach Dabo Swinney. Notre Notre is 4-3 SU and 3-4 ATS in playoff games coached by Brian Kelly.

The Tigers are 10.5-point favorites against the Crimson Tide.

Notre Dame is favored to beat Clemson 45.8-31.0 in the Cotton Bowl.

Notre Dame won the season opener against Michigan 24-17. The Irish beat seven teams that made the CFP this season to secure their first-ever berth in the college football playoffs. They are 8-0 SU and 6-1-2 ATS with junior Ian Book as the starter at quarterback this year.

Clemson won all 10 games this season, including the ACC championship game against Pittsburgh. The Tigers are 9-0 SU and 6-3 ATS on the college football odds. They're also 5-1 ATCW when favored by three touchdowns or fewer.

The smart money takes the Irish and the points in Cotton Bowl. Clemson beat Florida State, Syracuse and Wake Forest by an average score of 50-12 this season. Notre Dame beat the Seminoles, Orange and Demon Deacons by average of 45-14.

Notre Dame is 13-0 SU in its last 13 games. Notre Dame has won all five of its games against the ACC. The total has gone over in six of Notre Notre's last eight games in December.