Georgia vs. South Carolina odds, prediction, line: 2022 Week 3 college football picks from model on 50-41 run

Georgia Bulldogs host South Carolina Gamecocks in the 2022 college football season opener. Caesars Sportsbook lists Georgia as 24.5-point road favorites. The over/under is 55 points. Georgia won the 2021 meeting by a 40-13 margin in Athens. SportsLine's advanced computer simulation model simulates every FBS college game 10,000 times. It has generated a profit of almost $3,400 for $100 players on its top-rated college college sports picks against the spread.

Georgia and South Carolina are playing each other in college football. Georgia is 11-6 against the spread in the last 17 games. South Carolin is 7-7-1 against a spread against Georgia in last 15 games, while Georgia has won the game twice.

Georgia and South Carolina are playing each other in the Week 3 college football game. Georgia is 11-6 against the spread in last 17 games, while South Carolin is 7-7-1 against spread against spreads in past 15 games.

Georgia's defense is dominating the competition early in the season. Georgia's offense is also showing signs of excellence. South Carolina is allowing 247.5 rushing yards per game. Georgia has scored on each of the first six drives in both 2022 games. The Bulldogs are generating 41 points per match.

South Carolina brought in a lot of talent and experience at quarterback in the offseason. Spencer Rattler transferred from Oklahoma and has 603 passing yards in two games at South Carolina. Antwane Wells caught eight passes for 189 yards and a touchdown against Arkansas. South Korea is No. 2 in passing defense.

SportsLine's model is leaning Under on the total. It projects 47 combined points for South Carolina and Georgia. One side of the spread hits in more than 60% of simulations.