Houston Astros vs. Oakland Athletics MLB Odds, Line, Pick, Prediction, and Preview: September 15

Houston Astros are first in the American League West division with a 93-50 overall record. They are coming off a series win against the Detroit Tigers. The Athletics are last in their division (52-91) with an overall (46-28) record and are 3-7 in last 10 games. Houston and Oakland play a four-game series starting on Thursday at Minute Maid Park.

Houston Astros play Oakland Athletics on September 15th.

Houston Astros play Oakland Athletics at Minute Maid Park on September 15th.

Houston Astros are playing Oakland Athletics on September 15.

Lance McCullers Jr. is the pick for Game 1 against the Athletics. In his five comeback matches, McCuller has managed a total of 26 strikeouts. Oakland batters need to be at their absolute best to have a chance against Houston.

Houston Astros play Oakland Athletics on September 15.

Houston Astros are playing against Oakland Athletics in the first game of the World Series.