Houston Astros vs. Seattle Mariners Picks, Predictions & Odds

There are some big MLB games on the MLB schedule on Friday night, including a huge rivalry matchup in the AL West. The Seattle Mariners host the Houston Astros, and both teams are looking to get things rolling. 

The MLB standings in the AL West are expected to be tight all season long, and every game will matter. Both teams have a great starting pitcher on the mound in this one. And that will make it an even better showdown. 

Here is some key information that can help you make Astros vs Mariners picks on Friday night in the series opener. 

Houston Astros vs Seattle Mariners

Location of the game: T-Mobile Park, Seattle, WA.

Date & Time: Friday, May 5, 10:10 PM EST.

How to watch: ESPN+

The first thing to look at when making Astros vs Mariners picks are the odds that are available for this matchup.

Seattle is the moneyline betting favorite at -130 for this game, and the over/under is set at 7.0 total runs. 

You can also find some player props or run-line betting options, but those are the best odds to look at. 

The Houston Astros odds to win the World Series have taken a big hit since the season began. This team has gone just 16-15 to begin the year. Houston still has a chance to turn things around, but they have struggled in the power department this season. 

The Astros have hit just 28 home runs this season. But they have managed to stay in the race thanks to some great pitching. Houston has a team ERA of just 3.20 this season. That is going to be a big key in this matchup. 

Teoscar Hernandez has some impressive MLB player stats this season as he leads the Mariners with seven home runs. Seattle is a team that can put up some runs in a hurry. Jared Kelenic is having a huge season as well. 

The Mariners have also done a great job of getting outs, as they are pitching to a team ERA of just 3.44. Seattle has been trying to get past the Astros in recent years, and there is pressure on them to deliver in this series. 

The MLB injury report is long when it comes to the starting rotation for the Houston Astros, and that puts a ton of pressure on Cristian Javier. The right-handed pitcher has gone 2-1 with a 3.48 ERA to begin the season, but he will have to be at his best in this matchup.

Javier did get hit around a bit in his last start as he gave up seven hits and three earned runs in 5⅔ innings. 

It’s usually a good thing to bet on Seattle Mariners games when Luis Castillo is set to take the ball. Castillo has gone 2-0 with a 1.82 ERA this season, and he has been nothing short of sensational since joining the Mariners a season ago. 

There is always a temptation to make several MLB picks for just one single game, but that’s not what your focus is for this game. These are two pretty evenly matched MLB teams, and both are hoping to get their season turned around.

Even though there are some great pitchers on the mound in this game, this is going to be a game in which five runs are needed. If you are going to be making Astros vs Mariners picks, then you will want to bet on the over 7.0 total runs and take the home team to win this game outright.

• Over/Under: Over 7.0 Runs
• Moneyline: Seattle Mariners -130

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