MLB odds: Guardians-Red Sox prediction, odds, pick

The series between Boston and Cleveland is the second this season. Boston won the first one in Cleveland last month. The Red Sox have lost all three games since the All-Star break. Cleveland has lost back-to-back games after winning five consecutive games.

Cleveland and Boston are playing a game. The game is going to be decided by the quality of the opposing pitchers. Cleveland has a better ERA than Boston. Jose Ramirez is a big threat against right-handed pitchers, and he's the best against them in MLB.  Cincinnati has the better team in the late innings. Boston has an even better record in this area.

The Red Sox were outscored 40-10 over the weekend. Pivetta's record against the Guardians is promising. Plesac has been more productive in July, but his last 14 2/3 innings are not very impressive. The Red Sox have a significant advantage at home games. They rank fifth in MLB in OPS and slugging percentage. Their .266 batting average is the third-best in baseball.

Guardians are a long shot to cover -1.5 with only +146 on the juice. Boston is a team that has lost five straight. Cleveland is the play here.

Guardians are picking against the Red Sox.