Nuggets vs. Cavaliers prediction, odds, line: 2023 NBA picks, Jan. 6 best bets from proven computer model

Denver Nuggets host the Cleveland Cavaliers on Friday at 9 p.m. ET. Denver is 15-3 at home and 7-10 on the road. The Nuggets are coming off a blowout 122-91 win over the Los Angeles Clippers. Cleveland is riding a three-game winning streak. Donovan Mitchell and Darius Garland are out for Cleveland. SportsLine's computer simulation model simulates every NBA game 10,000 times and has returned well over $10,00 in profit for $100 players on its top-rated NBA picks over past four seasons.

SportsLine's computer model has made its picks and NBA predictions for Denver Nuggets vs. Cleveland Cavaliers. The model is using the Denver -6 spread and the money line of Denver to pick the winner.

Nuggets vs. Cavaliers is a 2023 NBA game. The Nuggets are 6-6 favorites.

Denver Nuggets beat the Los Angeles Clippers 122-91 on Thursday. Jamal Murray (18 points), Nah'Shon Hyland (16 points) and Nikola Jokic (12 points, 12 assists, 6 rebounds) were the top scorers for Denver. JOKic is averaging 25.2 points and 10.7 rebounds this season.

Cleveland Cavaliers beat Phoenix Suns 90-88 on Wednesday. Denver Nuggets are a tough team at Ball Arena. Donovan Mitchell will be rested. Darius Garland is injured. Evan Mobley and Jarrett Allen will need to perform well to give the Cavs a chance.

The model simulates Nuggets vs. Cavaliers 10,000 times and it's picking the Nuggets. SportsLine's model is leaning Over on the point total and has a point-spread pick that's hitting in almost 70% of simulations.