Ohio State vs. Indiana Prediction, Odds, Lines, Spread, and Picks- November 12

The Ohio State Buckeyes are preparing for their end-of-season clash against their arch-rival Michigan Wolverines. The Buckeye are currently on a 9-0 winning streak. They have to beat the Indiana Hoosiers first before they turn their attention towards Michigan.

Ohio State Buckeyes are the favorite to win the game against Indiana. C.J. Stroud has been outstanding for the Buckeye offense this season. Jaxon Smith-Njigba is back and should be able to help Stoudt. Marvin Harrison Jr. continues his development as a receiver with over 800 yards receiving and ten touchdowns. Emeka Egbuka has just under 800 receiving yards and seven touchdowns for Sturdon. TreVeyon Henderson and Miyan Williams are dynamic back-up running backs for Ohio State.

Ohio State Buckeyes host Indiana Hoosiers on November 12.

Ohio State vs. Indiana is on Saturday, November 12 at 12:00 PM ET at Ohio Stadium in Columbus, Ohio.

Ohio State Buckeyes are going to take an early lead and wear down the Hoosiers' defense. The Buckeye offensive line should open up wide holes for TreVeyon Henderson to exploit.

Ohio State Buckeyes are favored by three scores over Indiana Hoosiers.