Orange Bowl Odds: Tennessee-Clemson prediction, odds and pick

The Orange Bowl is on Friday at 8 pm ET. Tennessee Volunteers (10-2) take on the Clemson Tigers (11- 2) who finished second in the SEC East. Both teams are traveling a lot.

Tennessee is playing in the Orange Bowl. The Volunteers are the most prolific offense in college football, but they are vulnerable on defense. Tennessee will be without quarterback Hendon Hooker and wide receiver Jalin Hyatt and Cedric Tillman. They will rely on their run game, especially with the injury to quarterback. Jaylen Wright and Jabari Small are Tennessee's top two rushers. Clemson is the 11th-ranked rush defense in terms of YPG.

Clemson is 25th in the country in scoring (34.7 PPG) and 53rd in total offense (405 YPG). They are stout defensively, ranking 19th and 25rd respectively. Clemson's offense is balanced and runs the ball 53% of the time. Sophomore Will Shipley rushed for 1,110 yards and 15 touchdowns this season. True freshman Cade Klubnik started his first career game in ACC Championship game. He completed 20-24 passes for 279 yards.

Clemson looked like a different team after their quarterback change. I like them to handle Tennessee with ease based on how the Volunteers played down the stretch.

Clemson Tigers are favored to beat Tennessee at the Orange Bowl.