Real Madrid vs Liverpool odds, picks and predictions

Real Madrid welcomes Liverpool to the Santiago Bernabeu in the 2nd leg of the UEFA Champions League Round of 16. Kickoff is set for 4 p.m. ET. Below, we preview Tipico Sportsbook's lines around the Real Madrid vs. Liverpool odds, and make our best Champions League bets, picks and predictions.

Real Madrid beat Liverpool 5-2 on Feb. 21 in the 1st leg at Anfield. They did have fewer expected goals though, 1.6 vs. 1.8.

Real Madrid is coming off a 3-1 home win over Espanyol and sits 2nd in La Liga. They are unbeaten in 12 matches at home, posting 8 wins and 4 draws. Real averages 2 goals per game and has allowed .76 in league play. They were 4-1-1 in the Champions League group stage.

Liverpool posted 5 wins and a loss in the group stage, but had a worse goal differential than Napoli. Liverpool has a steep hole to climb out of, and they'll have to do it with just a 3-7-3 road record, having tallied just 12 points in 13 away EPL matches. Liverpool is led by star F Mohamed Salah, who has 11 goals in 26 starts.