Sam Houston vs. Liberty odds, line, picks: Predictions for Thursday's college football Week 6 matchup from advanced computer model

The Liberty Flames host the Sam Houston Bearkats on Thursday night in a Conference USA college football Week 6 matchup of teams on opposite trajectories. The Flames (4-0) have one of the nation's top offenses and have won all four games by double digits in their C-USA debut season. Sam Houston (0-4) has struggled to score points and is seeking the first victory of its inaugural campaign at the FBS level.

Kickoff is set for 7 p.m. ET at Williams Stadium in Lynchburg, Va. The latest Sam Houston vs. Liberty  odds list the Flames as 18-point favorites, and the over/under for total points scored is set at 46.5. (head to SportsLine's college football odds page for the latest odds on every game).

Before you make any Liberty vs. Sam Houston picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

The model knows the Flames have been dominating on offense behind quarterback Kaidon Salter and a potent running game. Salter has 919 passing yards, with 11 touchdowns and one interception. He is second on the team with 268 rushing yards and has run for five scores. Liberty is rushing for 271 yards per game, second in FBS, with backs Quinton Cooley (323 yards) and Billy Lucas (244) both averaging more than 6 yards per carry.

The model also has considered that the Bearkats come off their best offensive performance last Thursday, and they had a week to rest. Quarterback Keegan Shoemaker threw for 285 yards and two touchdowns in the 35-28 overtime loss to Jacksonville State. Running back John Gentry had a 56-yard touchdown catch and rushed for 97 yards, while receiver Noah Smith had 10 catches for 97. The Bearkats finished with 435 total yards.

Now, the model has set its sights on Thursday's Sam Houston vs. Liberty matchup. We can tell you it is leaning Over on the total, and it also says one side of the spread is hitting more than 60% of the time! You ABSOLUTELY need to see it before locking in any college football picks!