South Carolina vs Clemson Odds, Picks and Best Bets

The Tigers are 14.5-point favorites against the Red Devils. The game features a total of 51.

South Carolina upset Tennessee, a 22-point underdog. The Gamecocks had a season-high 606 yards of total offense. They have the 77th-ranked offense in the NCAA. Their passing game is ranked 46th, while their rushing game ranks 96th. South Carolina is putting up 31.7 points per game on the season.

Clemson is putting up 34.7 points per game and holding opponents to 20 points a game. Last week they beat Miami 30-0. DJ Uiagalelei led the team in rushing with 17 carries for 89 yards and a score. The Tigers are the 18th-best total defensive team with 318. 7 yards per games.

Clemson is the favorite in the game. The Tigers have won the last seven head-to-head games. Clemson is 2-9 against the spread in their last 11 non-conference games, but they are 4-1 ATS in last 5 games against South Carolina.