UFC 281: Adesanya vs. Pereira fight week schedule, full card, predictions, and betting odds

The UFC is headed to Madison Square Garden in New York City for its next pay-per-view card, UFC 281: Adesanya vs. Pereira. Headlining the card is a middleweight title showdown between defending champion Israel Adeganyana and his former kickboxing foe Alex Pereir. The co-headlining event is between reigning 115-pound queen Carla Esparza and former titleholder Weili Zhang.

The pre-fight press conference for UFC 281: Adesanya vs. Pereira will take place on Thursday, November 10. The event will be broadcast live on the promotion's official website, YouTube, Facebook, and Twitch accounts.

Official and ceremonial weigh-ins for the UFC 281: Adesanya vs. Pereira event will take place on Friday, November 11.

Israel Adesanya is the favorite against Alex Pereira.

Carla Esparza is the favorite against Zhang Weili at UFC 281.

Dustin Poirier is the favorite against Michael Chandler.

Frankie Edgar is the favorite against Chris Gutierrez.

Dan Hooker is the favorite against Claudio Puelles at -170.

Brad Riddell is +105 and Renato Moicano -125.

Dominick Reyes is the favorite against Ryan Spann.

Erin Blanchfield is the favorite against Molly McCann.

Andre Petroski is the favorite against Wellington Turman at UFC 281.

Matt Frevola is the favorite against Ottman Azaitar.

Karolina Kowalkiewicz is the favorite against Silvana Gomez Juarez.

Michael Trizano is +135 and Choi Seung-Woo -155 as the betting odds for UFC 281.

Julio Arce is +175 and Montel Jackson -205 at UFC 281.

Carlos Ulberg is the favorite against Nicolae Negumereanu.

Dan Hooker is coming off a first-round knockout loss to Arnold Allen at featherweight in March earlier this year. He will move back up to 155lbs and take on Claudio Puelles. PUELLES has won 5 of his last 5 fights by submission.

Frankie Edgar is set to make his 30th appearance in the UFC at UFC 281 on Saturday. Frankie Edgar has gone 1-4 in his last five fights and suffered back-to-back knockout losses in last two. Chris Gutierrez is unbeaten in seven fights. Gutierrez's latest victory came against Batgerel Danaa.

Dustin Poirier and Michael Chandler are going to fight at UFC 281. Poier lost to Charles Oliveira in December, whereas Chandler won against Tony Ferguson in May. The fight is expected to take place on the feet.

Carla Esparza is defending her UFC title against Zhang Weili. Weilil won her last fight against Joanna Jedrzejczyk. She is expected to have an advantage in terms of takedown defense and striking.

Israel Adesanya is the current UFC middleweight champion. He beat Jared Cannonier at UFC 276 in July. His opponent Alex Pereira is a former Glory Kickboxing champion who has 21 knockout victories and five finishes on his 6-1 MMA resume. Pereiras is relatively new to MMA and doesn't have the experience of other top contenders in the division.