Virginia vs Syracuse Odds and Picks

Syracuse will try to start a season 4-0 for the first time since 2018 when it hosts Virginia at 7 p.m. ET on Friday. Syracuse beat Purdue 32-29 last Saturday at home. Virginia won 16-14 over visiting Old Dominion on a game-ending field goal.

Syracuse is -375 on the moneyline in the college football odds. In the ACC championship odds, Syracuse is listed at +5000 and Virginia at -12000. The game will be played indoors.

Virginia beat Old Dominion last Saturday. Brendan Farrell kicked a 26-yard field goal as time expired. Brennan Armstrong drove Virginia 56 yards to the winning field-goal. The Cavaliers outgained Old Dominick 513-324 but lost three fumbles. Keytaon Thompson is Virginia's top receiver with nine catches for 118 yards.

Syracuse won the game against Purdue. Garrett Shrader threw a 25-yard touchdown pass to Oronde Gadsden II with seven seconds left. Two penalties forced Purdue to kick off from the 10-yards line. Shrerader completed 13 of 29 passes for 181 yards, three touchdowns and no interceptions.

Virginia leads the all-time series 3-2. Virginia won 44-38 in triple overtime in the last meeting during the 2015 season in Charlottesville. Syracuse is 3rd in their conference and is flying under the radar nationally.