2022 MLB odds, picks, bets for Wednesday, June 22 from proven model: This four-way parlay pays almost 15-1

Minnesota Twins host the Cleveland Guardians on Wednesday at 7:40 p.m. ET. The game is one of 15 on the MLB schedule for Wednesday. Tyler Anderson and Tony Gonsolin are the only nine-win pitchers in the majors. Shohei Ohtani is trying to win three straight starts for the first time this season when the Angels host Royals. SportsLine's prediction model simulates every MLB game 10,000 times and it's on a 56-47 roll on top-rated MLB money-line picks through 11 weeks.

Pittsburgh is taking Pittsburgh (+115) to beat the Cubs for the third straight day at 7:05 p.m. ET. Pittsburgh won the first game of the series on Monday, 12-1. On Tuesday, Pittsburgh pounded the Chicago Cubs 7-2. Chicago has lost 13 of 15 games in June.

The model has selected a four-way parlay with a payout of almost 15-1 for Wednesday, June 22. It also has three other best bets for the model.