Best Over/Under Bets for NFL Week 1: Injuries a Factor as Regular Season Kicks Off

The 2022 NFL regular season kicks off this weekend. All 32 teams made significant personnel moves during the offseason. Oddsmakers are setting game line odds, including Over/Under totals.

Injuries are a factor in NFL Week 1 bets.

Ravens are without rusher Gus Edwards, tackle Ronnie Stanley and cornerback Marcus Peters. New York Jets are also without Zach Wilson. Joe Flacco will be forced to play quarterback if Wilson can't go. Ravens-Jets is a bettors' favorite.

Green Bay Packers and Minnesota Vikings are playing in the season-opening divisional clash. Davante Adams' departure leaves a void in Aaron Rodgers' offense. Injuries to Allen Lazard, Christian Watson and Robert Tonyan make it difficult for the Vikings to score early.

Buccaneers-Cowboys is a game to bet on. The game is under the odds. There are concerns about the health of the Tampa Bay offensive line and the Dallas receiving corps.

Best Over/Under bets for NFL Week 1 are available at SportsbookReview.com.

Best Over/Under Bets for NFL Week 1: Injuries a factor as Regular Season Kicks Off. Over-under picks made 9/6/2022 at 5:51 p.m. ET.