Bills vs. Lions Same Game Parlay Picks: Start Thanksgiving with a Big Payout

The Detroit Lions have lost five straight Thanksgiving games. This year, Detroit faces a Buffalo Bills team that's won twice in a row on the holiday.

The Lions are underdogs against the Bills on Thursday. Detroit has won its last two games.

Bills vs. Lions Same Game Parlay Picks: Start Thanksgiving with a Big Payout.

Lions are favored by 9 points against the Bills on Thursday afternoon. FanDuel Sportsbook offers a split of -118/104 on the Detroit side. Bills are struggling after a good start to the season. The Lions are 5-3 ATS as underdogs and 6-4 ATC this season and favored Thanksgiving teams are 35-16 AATS since 2004.

Bills running back Devin Singletary is the favorite to score a touchdown. The parlay has DraftKings and FanDuel picking him. Detroit's defense is ranked second in the NFL in rushing touchdowns allowed. The combined odds of the first two legs favor Draft Kings over Fanduel.

Buffalo has gone 4-2 in its last 6 games, but it's allowed four passing performances of 300-plus yards in that period. Jared Goff has been inconsistent this season, so the parlay is looking for a few extra yards from him to get him over 249.5 passing yards.

Brenden Schaeffer has covered the St. Louis Cardinals and Blues hockey for KMOV and co-hosts "The Big Show" on KTGR radio in Columbia, Missouri. Brenden has contributed to SBR since 2021, providing insights on MLB, NFL, NCAAF, and NBA.