Chargers at Chiefs Odds, Total and Best Bets for Thursday Night Football

The Chiefs and Chargers are AFC West rivals playing each other on Thursday night. DraftKings expects a high-scoring game with a 54.5 game total. The Chiefs are the home favorites by 3.3%. Patrick Mahomes threw for five touchdowns and 360 yards on the road against the Cardinals on Sunday. Justin Herbert threw 279 yards and three touchdowns against Oakland. Los Angeles run defense looked different from last season. The Chargers picked off Mahome twice last year. They also sacked him five times. In 2021, the Chargers and Chiefs will split the series. It's possible that the Chiefs could win the game.