Giants vs. Vikings odds, line, spread: 2023 NFL picks, Wild Card predictions, best bets from top model

The New York Giants (9-7-1) and Minnesota Vikings (13-4) are playing in the NFL Wild Card Weekend of the 2023 playoffs. Kickoff is set for 4:30 p.m. ET from U.S. Bank Stadium in Minneapolis. The Vikings won the regular season game against New Jersey 13-2. SportsLine's advanced computer model is simulating every NFL game 10,000 times and has returned well over $7,500 for $100 players on top-rated NFL picks since its inception.

Giants vs. Vikings is a game with a 48-point over/under. The money line is Minnesota -165, New York +140. Giants are 7-1 against the spread on the road.

Giants vs. Vikings money line is Minnesota -165, New York +140. Giants are 7-1 against the spread on the road.

The Giants had their best offensive performance of the season against the Vikings in Week 16. New York's ATS winning percentage this year (76.5%) is the fourth highest in the NFL for a single season in last decade.

Minnesota has been strong at home this season, with its lone loss coming against Dallas in Week 11. The Vikings have won five straight home games against the Giants, including their win three weeks ago. New York has only two wins in its last eight games, sneaking its way into the NFL playoff bracket.

The model simulates Giants vs. Vikings 10,000 times and it's leaning Over. One side of the spread cashes in more than 50% of simulations.