MMA Best Bets: Picks, Odds, and Predictions for UFC Vegas 61

The UFC returns to the Apex in Las Vegas on October 1st with a strawweight bout between Mackenzie Dern and Yan Xiaonan. John Castaneda is coming off back-to-back stoppage wins over Miles Johns and Eddie Wineland. He will now face Daniel Santos, who is 0-1 in the UFC. Both men are aggressive but Santos is slower and less effective than Castaeda.

Jesse Ronson is the underdog in his fight against Joaquim Silva. Silva has been knocked out twice in the UFC. Ronson has more power than Silva, but Silva's chin is a concern. John Castaneda is best bet at UFC Vegas 61.

Randy Brown is coming off three straight wins and is favored to beat Francisco Trinaldo. Trinalsdo has not been finished since 2017 and in his last 10 fights, eight of them have gone the distance. Brown lands 4.42 significant strikes per minute and Trinsida lands 3.15.

Randy Costa is coming off back-to-back losses and he switched camps. Randy Costa will beat Guido Cannetti. Mackenzie Dern will defeat Yan Xiaonan. The parlay is anchored by the main event. The best bet is Randy Brown by decision. UFC Vegas 61 is taking place on Saturday at the MGM Grand. It's a pay-per-view event with a purse of $100,000.

Mackenzie Dern and Randy Costa are the best bets for UFC Vegas 61.