Syracuse football vs. Purdue prediction and odds for week 3 college football

Syracuse football has started out the 2022 season on a high note, as the Orange walloped Louisville at home in week one and this past Saturday night, trounced UConn on the road. This coming Saturday afternoon, Syracuse football will welcome Big Ten Conference member Purdue to the JMA Wireless Dome.

FanDuel Sportsbook has installed Purdue as a 1.5-point betting favorite. The over/under was set at 58. 5 points and the moneyline for the Orange was -115.

Syracuse football is going to play Purdue in the third college football game of the season. Purdue won both games at home last season, but went 9-4 overall. Syracuse football picked up seven votes in this week's Coaches poll.

Syracuse football is expected to kick off versus Purdue at 12 pm on Saturday, Sept. 17. ESPN2 will provide television coverage. The Orange is 0-1 all-time against the Boilermakers. In 2004, Purdue destroyed Syracuse football, 51-0, in West Lafayette, Indiana.