UFC 270: Ngannou vs. Gane prediction, odds, picks: Best bets on the fight card from MMA expert

Francis Ngannou defends his UFC heavyweight title against Gane at UFC 270. Gne is a -160 favorite, while Ngansou is +140. Flyweight champion Brandon Moreno takes on Deiveson Figueiredo in the co-main event. MMA expert Marley has made 44 of his last 45 UFC 73 main-event picks. His followers have won more than $13,000. He also backed Calvin Kattar against Giga Chikadze at the UFC Fight Night.

Ngannou is the current UFC heavyweight champion. Gane is a 10-0 professional mixed martial arts fighter. Ngan nou has a five-fight win streak and is considered the most lethal striker in the UFC. Gneans is an experienced professional fighter who beat Lewis in August. SportsLine has an expert's pick for UFC 270.

Trevin Giles and Michael Morales are going to fight at UFC 270. Giles came to the UFC as an undefeated prospect in December 2017, but he suffered back-to-back losses. Morales is 21 and will make his UFC debut on Saturday.

Marley has strong picks for Ngannou vs. Gane and every other bout on the UFC 270 card. He's backing a fighter who has "looked amazing and pretty unbeatable" to emerge with a dominant victory.

Ciryl Gane is the underdog against Francis Ngannou in UFC 270. Brandon Moreno, Brandon, Moreno and Deiveson Figueiredo are also underdogs.