Week 1 NFL picks, odds, 2022 predictions, best bets from top expert: This three-way football parlay pays 6-1

Russell Wilson will play for the Denver Broncos against his former team Seattle Seahawks in the first Monday Night Football game of the 2022 season. Denver is favored by 6.5 points in Caesars Sportsbook's latest NFL odds. The Cowboys and Buccaneers will meet in a rematch of last season's game. Panthers quarterback Baker Mayfield will face his old team, the Browns. Expert Gary Hartstein is 427-344 on NFL side picks and 394-330 against the spread.

Hartstein likes the Chargers to cover against the Raiders. Los Angeles returns every key weapon from last season. The Chargers pass rush features Joey Bosa, Khalil Mack and Kyle Van Noy. The Raiders offensive line is a major question after the season-ending injury of Brandon Parker and the failure of 2021 first round pick Alex Leatherwood.

Hartstein has a three-way football parlay that pays 6-1. Hartstein also has two other spread picks, including one play fading a team that "could struggle initially."