2022 Arizona Bowl prediction, odds, line, spread: Ohio vs. Wyoming picks, best bets from proven simulation

Wyoming Cowboys and the Ohio Bobcats are playing in the 2022 Arizona Bowl on Friday at 5:30 p.m. ET. Wyoming is playing for the second straight year. Ohio played in a bowl game for first time since 2019. The Bobcat's are 2.5-point favorites. SportsLine's advanced computer simulation model simulates every college football game 10,000 times. It has returned a huge profit for its users.

Ohio vs. Wyoming is an Arizona Bowl in 2022. Ohio is 8-1 ATS in their last nine games overall. The Bobcats are also 4-0 AET in the last four bowl games.

Ohio vs. Wyoming is playing in the Arizona Bowl on December 22nd. Bobcats are 8-1 ATS in their last nine games overall and 4-0 AET in last four bowl games.

Sieh Bangura is the workhorse in the back-up for Ohio. Sam Wiglusz is a go-to receiver for Wyoming. He leads the team in receptions (69), receiving yards (850) and receiving touchdowns (11).

Wyoming's defense is solid, allowing 23.4 points per game with 149.7 yards on the ground. Easton Gibbs is a tackling machine who leads the team in total tackles (111) with two sacks. Shae Suiaunoa is another enforcer in the middle of the field.

SportsLine's model is leaning Over on the total. It projects 48 combined points for Wyoming and Ohio.