2022 MLB odds, picks, best bets for Wednesday, June 1 from proven model: This four-way parlay pays almost 13-1

The Los Angeles Dodgers host the Pittsburgh Pirates on Wednesday. Los Angles have the best record in the NL and have not been swept in any series this season. The Pirates have clinched the season series over the Dodgers for the first time since 2016. SportsLine's proven model simulates every MLB game 10,000 times and it's on a 48-31 roll on top-rated MLB money-line picks through eight weeks. It returned more than $1,100 for $100 players.

The model simulated each of the 16 games on Wednesday's schedule 10,000 times. It's taking San Francisco (+110) to defeat Philadelphia at 6:05 p.m. ET. The Giants (27-21) have been good on the road this season, going 14-10. Philadelphia (21-29) has struggled at home, and just four NL teams have worse at their home games.