2022 MLB playoff odds, Wild Card Series picks for Friday, Oct. 7 from top model: This 4-way parlay pays 10-1

The 2022 MLB playoffs begin on Friday with four Wild Card Series Game 1s. New York Mets and San Diego Padres are playing at Citi Field. Guardians host Rays, Blue Jays welcome the Mariners, and the Phillies visit the Cardinals. The over/under for runs scored is 6. SportsLine's computer model simulates every MLB game 10,000 times and has returned a payout of over 10-1 for parlaying four bets.

The model is backing the Guardians to beat the Rays in Game 1 of their Wild Card Series on Friday. The model ran 10,000 simulations on each of Friday's games. Cleveland won the Central division and claimed the No. 3 seed in the AL playoff bracket. Tampa Bay earned the third and final Wildcard berth with its third place finish in East.

The model has selected a 4-way parlay with a payout of 10-1 for Friday, Oct. 7. It also has three other best bets for that day, including a play that pays plus-money. SportsLine's model is on a 14-3 run on money-line picks.