76ers vs. Cavaliers odds, line, spread: 2022 NBA picks, April 3 prediction from proven computer model

The Philadelphia 76ers take on the Cleveland Cavaliers at 6 p.m. ET on Sunday. The 76er's are 3-0 against the Cavs this season. Philadelphia is favored by 4.5 points in the latest Cavaliers vs. 76ERS odds. SportsLine's advanced computer model simulates every NBA game 10,000 times and has returned well over $10,00 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons.

SportsLine's computer model has set its sights on Cavaliers vs. 76ers. The model is using its advanced computer algorithms to pick the winner.

Cleveland Cavaliers beat the New York Knicks 119-101 on Saturday. Darius Garland led the way with 24 points and 13 assists. Isaac Okoro scored 16 points on 7-for-8 shooting. The Cavaliers have shot 49.8 percent from the field and 33.7 percent on 3-point range in their previous three games against Philadelphia.

The 76ers won 144-114 against Charlotte on Saturday. Center Joel Embiid had a double-double with 29 points and 14 rebounds. Philadelphia is the fourth-best shooting team in the NBA and made 51.8 percent of its shots in last three games. Cleveland is 7-7 in second games of back-to-back games, while Philadelphia's 4-5.

The model simulates Cavaliers vs. 76ers 10,000 times and finds the model leaning under. It also has a point-spread pick that hits in almost 60 percent of simulations.