Knicks vs. 76ers prediction, odds, spread: 2022 Christmas Day NBA picks, best bets from model on 28-12 roll

Philadelphia 76ers and New York Knicks are playing each other on Sunday at noon ET. The 76er's have won 17 of the past 20 games against the Knicks. New Yorkers have lost two in a row. Philadelphia is a 2-point favorite in the odds from Caesars Sportsbook. SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,00 in profit for $100 players on its top-rated NBA picks over the last four-plus seasons.

SportsLine's advanced computer model has made its Christmas Day NBA picks. Knicks vs. 76ers is a 2-point favorite. The model is on a 28-12 roll.

Knicks vs. 76ers is a Christmas Day NBA game. The Knicks are 5-0 ATS in their last five games against a team with a winning % above .600.

The 76ers have won seven games in a row. Tobias Harris has been a key ingredient to the team's recent success. De'Anthony Melton has proven his versatility this year, and has made 21 starts in 28 appearances. He is averaging 12 points, 4.8 rebounds, 3.3 assists and 2.1 steals.

The Knicks are led by Julius Randle, who has scored in double-figure points in each of the last 16 games. R.J. Barrett had a season-high 44 points against the Bulls. In 33 games, all starts, Barrett is averaging 20.4 points, 5.5 rebounds and 3.6 assists.

SportsLine's model is leaning Over on the total and has generated an against-the-spread cashes in more than 50% of simulations.