Alabama vs. LSU odds, line, bets: 2022 college football picks, Week 10 predictions from proven computer model

Alabama Crimson Tide are favored by 13 points against the LSU Tigers. Kickoff is set for 7 p.m. ET. The over/under is 58. Alabama bounced back from a loss at Tennessee with a blowout win over Mississippi State. LSU has also bounced from the loss to the Vols with wins over Florida and Ole Miss. SportsLine's computer model simulates every FBS college football game 10,000 times and has returned a profit of almost $3,300 for $100 players on its top-rated college Football picks against spread.

Alabama and LSU are playing each other in the college football game on Saturday. The game is a favorite of Alabama.

Alabama and LSU play each other in a college football game on Saturday. The line is Alabama -13.5. LSU is +400 and Alabama is -550.

LSU has won six of its last seven games. The team's only loss came against now top-ranked Tennessee. LSU has covered the spread in five of last six home games and needs to keep the game within a couple of touchdowns to cash in tickets. Alabama has had some issues on the road this season, sneaking past Texas by one point before losing to Tennessee and then losing at home to Ole Miss.

Alabama has won 10 of the last 11 games between the two teams. LSU has only faced two ranked opponents this season, and one of them was a 27-point home loss to Tennessee. Alabama has gone 17-3 in its last 20 road games.

The model simulating LSU vs. Alabama 10,000 times has picked the over in almost 60% of simulations.