Best Colts vs Cowboys Same-Game Parlay for SNF

DraftKings Sportsbook offers Colts vs. Cowboys parlay with a profit boost of up to 100%.

Dak Prescott has looked fantastic since returning from his thumb injury. He's thrown for 250 or more yards in four consecutive starts, tossing 9 TD passes along the way. The Colts rank 13th per DVOA against the pass, while the Colts were a top-six graded run defense.

The Cowboys are the number one defense per DVOA and lead the league in pressure rate. The Colts are 31st on offense per the DVOA and have failed to exceed 18 points in eight of 12 games this season. Dallas has held Dalvin Cook and Saquon Barkley to 72 and 39 rushing yards in their past two games.

The Cowboys are 3-1 against the spread in their last four home games and 8-3 ATS overall. Dallas has won five games by 12 or more points this season. The Cowboys lead the league in cover margin at +7.2 points and are a league best 20-8 against against since the start of last season, as per the Colts vs Cowboys picks.

The Cowboys are a 10.5-point favorite against the Colts. DVOA has the teams graded 26 spots apart. The Colts and Cowboys have relatively few injuries.