Clemson vs. LSU Odds: Latest Betting Lines and Trends for College Football Playoff National Championship

Clemson and LSU are playing for the College Football Playoff national championship on Monday in New Orleans. LSU has gone 14-0 this season behind Heisman Trophy winner Joe Burrow. Clemson is one win away from defending the title it won 12 months ago against Alabama and from completing a 15-year unbeaten season.

Both teams are unbeaten this season. Clemson hasn't tasted defeat in 29 games. LSU is 8-3 straight up in games played in neutral venues since 2014.

LSU is a 5.5-point favorite and is 23/25 to cover the spread. Clemson is 11-3 against thespread this season and covered 78.6 percent of the games. The last time Clemson was the underdog, it beat Alabama 44-16 in the title game last year.

The over/under line for the total points scored is set at 69.5. The previous three meetings between LSU and Clemson produced a combined 73 points. Since the CFP inception in 2014, the national title game has produced an average of 64.4 points per game.