Cubs vs. Giants odds, tips and betting trends

At Wrigley Field on Wednesday, the San Francisco Giants meet the Chicago Cubs (three straight victories) at 2:20 PM ET.

The favored Cubs (-143 moneyline odds to win) host the Giants (+122). The Chicago Cubs will hand the ball to Jordan Wicks (2-0, 1.80 ERA), who is looking for win No. 3 on the season, and the Giants will turn to Alex Wood (5-4, 4.35 ERA).

The Cubs defeated the Giants 11-8 yesterday, with Drew Smyly getting the win (1.0 IP, 0 R, 1 H, 2 K) and Seiya Suzuki leading the way offensively (going 4-for-5 with a double, a home run and three RBI). Luke Jackson (0.2 IP, 4 R, 3 H, 2 K) took the loss for the Giants.

Ahead of the Cubs vs. Giants matchup, here is everything you need to get ready for Wednesday’s baseball action, including viewing options.

Chicago Cubs vs. San Francisco Giants Odds and Betting Lines

Tipico Sportsbook. Odds updated Wednesday at 9:19 AM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

• Favorite: Cubs (-143, bet $143 to win $100)
• Underdog: Giants (+122, bet $100 to win $122)
• Over/under: 10.5

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Cubs Stats and Trends

Cubs Betting Records

• The Cubs have been favorites in 76 games this season and won 46 (60.5%) of those contests.
• Chicago has entered 27 games this season favored by -143 or more and is 17-10 in those contests.
• The Cubs have a 58.8% chance to win this game based on the implied probability of the moneyline.
• So far this season, Chicago and its opponents have hit the over in 71 of 139 games with a total.
• In 139 games with a spread this season, the Cubs are 70-69-0 ATS.

Jordan Wicks (Cubs Probable Starter)

• The Cubs are sending Wicks (2-0) out for his third start of the season.
• His most recent time out was on Friday against the Cincinnati Reds, when the left-hander tossed five innings, surrendering one earned run while allowing five hits.
• In two games this season, he has put up a 1.80 ERA and averages 10.8 strikeouts per nine innings while opposing batters are hitting .194 against him.
• Wicks is aiming for his third straight outing lasting five or more innings. He averages five innings per appearance on the mound.
• The opposing Giants offense has the 26th-ranked slugging percentage (.385) and ranks 21st in MLB play with 149 home runs. It has a collective .237 batting average, and is 24th in MLB with 1106 total hits and 22nd in MLB play scoring 592 runs.

Cubs Batting Stats

• The Cubs’ 168 home runs rank 14th in Major League Baseball.
• The offense for Chicago has a slugging percentage of .419 this season, 13th in MLB.
• The Cubs’ .254 batting average ranks 12th in the league this season.
• Chicago has scored 708 runs this season, which ranks sixth in MLB.
• The Cubs have an on-base percentage of .329 this season, which ranks eighth in the league.
• Chicago ranks 18th with an average of 8.8 strikeouts per game.

Giants Stats and Trends

Giants Betting Records

• The Giants have come away with 32 wins in the 68 contests they have been listed as the underdogs in this season.
• This season, San Francisco has come away with a win 10 times in 26 chances when named as an underdog of at least +122 or longer on the moneyline.
• The moneyline set for this matchup implies the Giants have a 45% chance of walking away with the win.
• San Francisco and its opponents have hit the over in 58 of its 138 games with a total set by oddsmakers this season.
• The Giants are 65-73-0 against the spread in their 138 games with a line set by sportsbooks this season.

Alex Wood (Giants Probable Starter)

• Wood gets the start for the Giants, his 12th of the season. He is 5-4 with a 4.35 ERA and 63 strikeouts over 80 2/3 innings pitched.
• In his last appearance — in relief on Saturday — the lefty threw three innings against the San Diego Padres, giving up no earned runs while surrendering three hits.
• In 24 games this season, the 32-year-old has a 4.35 ERA and 7 strikeouts per nine innings, while allowing a batting average of .254 to opposing batters.
• So far this year, Wood does not have a quality start.
• Wood has pitched five or more innings in a game four times this year entering this outing.
• He is trying to keep a streak of five games without allowing an earned run intact.
• He will take the mound against a Cubs offense that ranks 11th in the league with 1197 total hits (on a .254 batting average). The team also slugs a collective .419 (13th in the league) with 168 total home runs (14th in MLB play).

Giants Batting Stats

• The Giants are 21st in baseball with 149 home runs. They average 1.1 per game.
• This season, San Francisco is slugging .385, the fifth-lowest percentage in the majors.
• The Giants are 25th in MLB with a .237 batting average.
• The offense for San Francisco is the No. 22 offense in MLB, scoring 4.3 runs per game (592 total runs).
• The Giants rank 23rd in baseball with an on-base percentage of .312.

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• Game Day: Wednesday, September 6, 2023
• Game Time: 2:20 PM ET
• Stadium: Wrigley Field
• TV Channel: Marquee Sports Network
• Live Stream: Fubo (Watch for free)