Detroit Lions vs New England Patriots Odds, Predictions and Best Bets for Week 5

Detroit Lions take on New England Patriots in a game that starts at 1:00 pm ET on FOX. The Lions (1-3) are tied with the league's top passing team with 18 touchdowns. New Patriots (3-1) have been uncharacteristically sloppy through three weeks.

Detroit Lions have one of the best offenses in the NFL. They are tied atop the league in passing TDs and are first in league with 18 total scores. The Patriots have been uncharacteristically sloppy through three weeks and they are looking for their second win.

The Patriots are three-point favorites against the Lions. The Patriots have been scoring 35+ points in three of their four games.

Mac Jones is getting in limited sessions this week. He skipped surgery on his high-ankle sprain. Backup quarterback Brian Hoyer is injured.

D’Andre Swift and Amon-Ra St. Brown are injured for the second-straight week. Josh Reynolds, TJ Hockenson, Frank Ragnow and Evan Brown all returned to practice this week after missing Wednesday. DJ Chark won't play on Sunday.

The expectations weren't high for Detroit following the Matthew Stafford/Jared Goff trade. The Lions finished with the seventh-lowest yards-per-attempt last season. This year they are the top-ranked offense.

The Patriots defense has done a good job to this point in the season. They held Aaron Rodgers to 251 yards and a pair of TDs last week. The Patriots struggled to contain the Packers on the ground, allowing AaronRodgers to rack up 110 yards.

Damien Harris and Rhamondre Stevenson had 86 and 66 yards on 18 carries in the last game. New England has the highest yards-per-carry at 5.6 and gives up 40 first downs via the run and 10 TDs.

The Lions have been scoring a lot recently. The Patriots will probably focus on the ground game. Detroit has played three defenses in the top ten for passing yards allowed.

Detroit Lions vs. New England Patriots is a game to watch for Week 5. The under 45.5 (-108) is the best bet.