Detroit Tigers at Cincinnati Reds odds, expert picks and prediction

Detroit Tigers and Cincinnati Reds are playing a three-game interleague series. First pitch is scheduled for 1:10 p.m. ET. The Tigers won Friday's game 15-5 and the Reds won Saturday 7-4. They are tied 1-1 in the season series, but the Tigers are the better team.

Last outing: Loss, 3-2, with 6 IP, 6 ER, 5 H, 1 BB and 4 K against the Minnesota Twins. Road stats: 4-3 with a 3.50 ERA (74 2/3 IP and 29 ER), 1.09 WHIP and 3 K/BB across 13 starts.

Last outing: Loss, 3-1, with 6 IP, 6 ER, 5 H, 2 BB and 8 K against the St. Louis Cardinals. 21st century home stats: 5-6 with a 3.57 ERA (80 2/3 IP and 32 ER), 1.38 WHIP and 2.8 K/BB over 14 starts.

Tigers at Reds odds, lines, picks and prediction.

Detroit Tigers are 7-5 as a road underdog when Mize gets the start. Cincy is just 10-18 straight up in games Castillo starts.

Detroit Tigers are 9-3 ATS as road underdogs with Mize starting and have a plus-29.4% ROI. Cincinnati is 4-6 ATC as home favorites with Castillo starting. The game is going to be played under 8.5 points.

There are bets on Tigers-Reds in September.