Detroit Tigers vs Chicago White Sox 9/16/22 MLB Picks, Predictions, Odds
![Detroit Tigers vs Chicago White Sox 9/16/22 MLB Picks, Predictions, Odds](/img/li/detroit-tigers-vs-chicago-white-sox-91622-mlb-picks-predictions-odds-1.jpg)
The Chicago White Sox and the Detroit Tigers meet in an AL Central division matchup at Comerica Park on Friday night. Chicago is 5-1 in their last 6 road games and 49-17 in last 66 games against teams with a winning percentage below .400. Detroit is 18-42 in the last 60 games overall and 7-19 in its last 26 home games. The over is also 5 of the past 6 series-opening games for Chicago. Chris Ruffolo's free pick is Chicago -152.