England vs Wales prediction and odds: Visitors could be surprise package after Scotland win
Wales beat Scotland 20-17 at the Millennium Stadium in round two of the Six Nations. England lost to Scotland at Murrayfield in the first round. They are favourites to win the match at Twickenham. A second defeat for either side would effectively end their Six nations campaign.
Wales beat Scotland in the Calcutta Cup. They play England at Twickenham on Saturday.
England vs Wales is a potential upset after Scotland's win. England are 2/13, Wales are 17/4.