Giants vs. 49ers Player Prop Bets for Thursday Night Football: Christian McCaffrey, George Kittle, Darren Waller, and Others

Tonight, we have a Thursday Night Football matchup between two NFC playoff teams from one year ago — the New York Giants and San Francisco 49ers.

The star power is on the 49ers’ side, with Christian McCaffrey, George Kittle, Deebo Samuel, and Brandon Aiyuk. For this Thursday Night Football matchup, how should we be approaching Giants vs. 49ers player prop bets? We break those down for tonight and give you our favorite plays.

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Top Giants vs. 49ers Player Prop Bets to Target

Our team of betting experts give out their favorite player prop bets for Giants vs. 49ers on Thursday Night Football.

All odds are from DraftKings Sportsbook unless noted otherwise.

Daniel Jones Player Props

• Passing Yards: 214.5 (Over -115/Under -115)
• Pass Touchdowns: 1.5 (Over +175/Under -230)
• Pass Completions: 19.5 (Over -130/Under +100)
• Pass Attempts: 32.5 (Over -110/Under -120)
• Interceptions: 0.5 (Over -115/Under -115)

Daniel Jones’ first two games couldn’t have been more different. He threw for 104 scoreless yards against the Dallas Cowboys and 321 yards with two touchdowns against the Arizona Cardinals. That makes figuring out his props quite a challenge.

The 49ers defense is definitely closer to the Cowboys than the Cardinals. I certainly wouldn’t take any Jones overs, but Matthew Stafford was able to throw for 307 yards against this defense. I worry that if we take any of his unders, he could garbage-time his way into hitting. As a result, I am passing.

Matt Breida Player Props

• Rushing Yards: 32.5 (Over -115/Under -115)
• Receiving Yards: 12.5 (Over -110/Under -120)
• Receptions: 2.5 (Over +135/Under -175)
• Longest Rush: 10.5 (Over -120/Under -110)
• Anytime Touchdown Scorer: +240
• First Touchdown Scorer: +1600

Matt Breida has exactly one game in a feature role since 2018. It was Week 18 of last season with the Giants resting starters … he saw four carries.

Breida will be the lead back, but this is an awful matchup. I’m expecting a bit of a timeshare with Gary Brightwell and possibly Eric Gray, too. Plus, even if I’m wrong, I can certainly envision Breida taking 10-12 carries and going nowhere with them.

Pick: Matt Breida under 32.5 rushing yards (-115)

Darren Waller Player Props

• Receiving Yards: 46.5 (Over -115/Under -115)
• Receptions: 4.5 (Over +124/Under -160)
• Longest Reception: 19.5 (Over -105/Under -125)
• Anytime Touchdown Scorer: +265
• First Touchdown Scorer: +2000

I am very nervous about Darren Waller and his hamstring playing on a short week. While it’s only been two weeks, just 6.3% of the receiving yards allowed by the 49ers have gone to tight ends.

With that said, Waller isn’t your typical tight end — he’s the Giants de facto WR1. This is another tricky situation where it’s under or bust. Given the performance of tight ends against the 49ers, I’m OK giving out a lean here.

Lean: Darren Waller longest reception under 19.5 (-125)

Brock Purdy Player Props

• Passing Yards: 230.5 (Over -115/Under -115)
• Pass Touchdowns: 1.5 (Over -120/Under -110)
• Pass Completions: 20.5 (Over +105/Under -135)
• Pass Attempts: 28.5 (Over -125/Under -105)
• Interceptions: 0.5 (Over +190/Under -250)

Brock Purdy’s multi-touchdown streak came to an end last week when the Los Angeles Rams held him scoreless through the air. I do think he will bounce back this week. The 49ers will likely score at least four touchdowns.

There’s always a risk Christian McCaffrey runs in three of them, but the Giants defense has looked like one of the worst in the league, getting smoked by Joshua Dobbs and the Cardinals last week.

Lean: Brock Purdy over 1.5 passing touchdowns (-120)

Christian McCaffrey Player Props

• Rushing Yards: 79.5 (Over -130/Under +100)
• Receiving Yards: 29.5 (Over -115/Under -115)
• Receptions: 3.5 (Over -175/Under +135)
• Longest Rush: 17.5 (Over -115/Under -115)
• Anytime Touchdown Scorer: -200
• First Touchdown Scorer: +320

It appears the 49ers did not care that they had a Thursday game coming up, as they played McCaffrey on 100% of the snaps last week. Head coach Kyle Shanahan might not have realized it at the time, but after the game, he insinuated that McCaffrey is probably out there too much.

On a short week, I’m expecting McCaffrey’s snap share to drop into the 70-80% range. He will still dominate, but Elijah Mitchell should not only see the field but see some actual carries.

The 49ers could completely dominate this game, leading to a ton of running opportunities. As a result, I am not confident enough to make this an official pick. But I do have a lean.

Lean: Christian McCaffrey under 17.5 rush attempts (-115 BetMGM)

Deebo Samuel Player Props

• Receiving Yards: 53.5 (Over -115/Under -115)
• Receptions: 4.5 (Over -125/Under -105)
• Longest Reception: 21.5 (Over -110/Under -120)
• Anytime Touchdown Scorer: +120
• First Touchdown Scorer: +650

2021 Samuel made an appearance last week. His receiving role did not change from Week 1, but he carried the ball five times for a very efficient 38 yards and a touchdown.

It’s going to be very hit or miss for Samuel on a weekly basis in terms of his usage. However, with Brandon Aiyuk banged up, his role could be more stable this week.

Given that Shanahan wants to lighten McCaffrey’s load a bit, perhaps we see more of Samuel out of the backfield. Either way, I think he has a big game.

Lean: Deebo Samuel over 15.5 rushing yards (-110)

George Kittle Player Props

• Receiving Yards: 43.5 (Over -120/Under -110)
• Receptions: 3.5 (Over -150/Under +120)
• Longest Reception: 10.5 (Over -110/Under -120)
• Anytime Touchdown Scorer: +175
• First Touchdown Scorer: +900

Kittle is probably the best tight end in football. Unfortunately, we can’t win any bets based on his blocking prowess. From a receiving standpoint, while clearly super talented, he’s just a guy out there. The 49ers make no deliberate effort to get him the ball.

Kittle saw just three targets last week. That was after seeing six in the opener. He has six catches for 49 yards on the season.

There will inevitably be a couple of games where Kittle absolutely smashes. In those games, he will put up something like five catches for 90 yards and two touchdowns.

Since we have no idea when those games are, rather than try and guess on a standard prop bet, let’s take a shot on long odds.

Longshot Play: George Kittle first touchdown (+1100 BetMGM)

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