Houston Astros at San Diego Padres odds, expert picks and prediction

Houston Astros and San Diego Padres are playing a three-game series finale at Petco Park. First pitch is scheduled for 4:10 p.m. ET. Luis Garcia is Houston's projected starter. Chris Paddack is the Padres' starting pitcher. SanDiego won the first game 10-2.

Houston's last outing was Monday in the 4-3 victory at Seattle. He had a no-decision. Road splits are 4.3 with a 4,85 ERA (59 1/3 IP, 32 ER), 1.37 WHIP and 2.9 K/BB in 12 starts.

Last outing: No-decision with 4 2/3 IP, 1 ER, 3 H, 0 BB and 5 K in San Diego's 7-5 victory at Arizona Diamondbacks Monday. Home record: 3-4 with a 6.59 ERA (42 1/2 IP and 31 ER), 1.68 WHIP and 3.8 K/BB in nine starts and one bullpen outing.

Houston Astros are playing San Diego Padres.

The Padres are 12-5 in interleague games and the Astros are 7-9. The Padres beat the Houston Astros 5-3.

The Padres are favored to win. The odds are slightly under -150. Sportsbooks want more pro-Over bets. The total is down from the flat-9. Houston Astros are playing San Diego Padres. Fantasy Baseball:BaseballHQ.com predicts the Padres to dominate the competition.