Houston Astros vs. Boston Red Sox Odds, Analysis, MLB Betting Pick

The Boston Red Sox and Houston Astros are playing a pick'em game on Friday at Fenway Park. The teams are going for a rematch of last year's American League Division Series. Houston won four of five games last October to win the World Series, while Boston won the other four games.

Houston Astros are the favorite against Boston Red Sox at sportsbooks. The total is 8.5 runs.

Houston Astros are the favorite against Boston Red Sox at the sportsbook.

Houston has 10 fewer wins than Boston, but it's on a five-game winning streak and leads MLB with a plus-235 run differential. Gerrit Cole has been a nice addition to Houston's starting rotation in 2018, and he has gone 3-0 in his past four starts.

The Boston Red Sox have won three straight games. They have the best home record in MLB at 48-18. David Price has been outstanding since the All-Star break, going 4-0 with a 1.62 ERA in seven starts.

Houston Astros and Boston Red Sox are playing each other on Friday. The winner will be the winner.

Houston is 8-16 in its last 24 games on the road against Boston. Boston is 4-1 in their last five games. The total has gone under in five of Houston's last seven games and under is the favorite in this game.