Los Angeles Angels vs. Houston Astros: Odds, Analysis, MLB Betting Pick

The Los Angeles Angels are on the road for the first of three games against the Houston Astros. The Angels finished their six-game homestand at 1-5 after a 4-2 loss to the San Francisco Giants on Sunday. Houston has taken over the lead in the American League West with a six game winning streak.

The Houston Astros are the favorite at sportsbooks. The total is at eight runs.

Los Angeles Angels are the underdogs against Houston Astros. The over-under is 5.7-2.1.

The top two teams in the AL West will meet for the first time this season. Last year, the Angels went 7-12 in 19 games between the teams. Tyler Skaggs will try to bounce back from his worst start last time out against the Boston Red Sox.

Gerrit Cole has had a great start to the season for the Houston Astros. They are 4-0 after a rough stretch in which they lost five of six games.

Los Angeles Angels are the underdogs against Houston Astros at Minute Maid Park. The Angels were underdog of -145 or higher in all of their four wins there last season. Houston has a lethal lineup and Cole has been outstanding this year.

Los Angeles is 8-1 ATS in its last nine games on the road. Houston is 5-0 AET in the last five games. The total has gone over in four of Houston's last 5 games against the Angels.