Kansas vs. Iowa State odds, spread, lines: Week 5 college football picks, predictions

Kansas is undefeated through four games for the first time since 2009. Iowa State is 3.5 points favorites to beat Kansas. The College Football Power Index computer prediction model projects Iowa state to win. Iowa is expected to be 9.6 points better than its opponents on average week to week. It has 86.3 percent chance to play in a bowl. KU is ranked No. 55 on the index's 131 college football rankings. They are ranked 26th in the AP poll. In-state rival Kansas State came in at No 25. FuboTV provides full coverage of the top college games this season.