USC vs. Arizona State odds, spread, lines: Week 5 college football picks, predictions

USC is undefeated in the season and is the favorite to beat Arizona State in Saturday's game at the Coliseum. The computer predicts the Trojans to win 10.8 games on the way to the College Football Playoff. Arizona has a 6.3 percent chance to upset Southern Cal. The oddsmakers agree and the lines at SI Sportsbook set the over/under at 62.5 points for the matchup. AP voters moved Southern California up 1 spot to No. 6 in official polls for Week 5. It is in position to move into the top 4 if it stays perfect the rest of the year.