Liverpool vs Real Madrid live stream, TV channel, lineups, betting odds for Champions League clash

Liverpool's 2022/23 Champions League campaign restarts this week as they welcome old foes Real Madrid to Anfield for a Round of 16 first leg.

The Reds have faced the Spanish giants four times under Jurgen Klopp — with no wins — and defeats in the 2018 and 2022 finals to show for their efforts.

Klopp faces a huge battle to force his side into the quarterfinals over two legs with Carlo Ancelotti looking to win the competition for the fifth time as a coach.

Here's all the key information on the match including kickoff time, live streaming and TV channels, lineups and betting odds.

What time is Liverpool vs Real Madrid kick off?

This Champions League clash kicks off at Anfield on Tuesday, February 21 at 8:00 p.m. local time.

Here's how that time translates across some of the major territories:

Liverpool vs Real Madrid live stream, TV channel

Here's how to watch all of the action from this match in some of the major territories:

Australia: Fans can watch every match of the UEFA Champions League with all the action streaming ad-free, live and on demand on Stan Sport.

Canada: Every Champions League match in Canada can be streamed exclusively on DAZN. 

UK: The UEFA Champions League is carried by BT Sport's TV and streaming platforms.

USA: Fans in the USA can watch the Champions League in English (CBS and Paramount+) and Spanish (Univision, TUDN, UniMas, ViX and ViX+).

When matches are televised on CBS or Univision channels, those same channels are streamed on fuboTV, which is available on a free trial for new users.

Liverpool vs Real Madrid lineups

Klopp has already confirmed Luis Diaz, Thiago Alcantara and Arthur Melo are all out for this game with Calvin Ramsey set to miss the rest of the season following surgery.

The major question mark for the hosts is on Darwin Nunez after he picked up a shoulder injury in the weekend win at Newcastle, with Klopp stating he has "a chance" to be fit in time. Diogo Jota is on standby to replace the Uruguayan.

Liverpool starting XI (4-3-3): Alisson (GK) — Alexander-Arnold, Matip, Van Dijk, Robertson — Henderson, Fabinho, Bajcetic — Salah, Gakpo, Jota

Liverpool subs: Kelleher (GK), Tsimikas, Philips, Gomez, Milner, Keita, Elliott, Firmino, Nunez

Ancelotti is without key midfield duo Toni Kroos and Aurelien Tchouameni for this clash with Fede Valverde and Eduardo Camavinga set to partner Luka Modric in the Los Blancos engine room.

Captain Karim Benzema is back in the squad after being rested for the weekend win over Osasuna, with Dani Carvajal also in line to start.

Real Madrid starting XI (4-3-3): Courtois (GK) — Carvajal, Militao, Alaba, Nacho — Valverde, Camavinga, Modric — Rodrygo, Benzema, Vinicius Jr

Real Madrid subs: Lunin (GK), Vallejo, Rudiger, Odriozola, Vazquez, Ceballos, Marin, Arribas, Hazard, Asensio, Rodriguez

Liverpool vs Real Madrid prediction, odds

Despite the prospect of a trip to the cauldron of Anfield, and the ongoing La Liga title race with Barcelona, Ancelotti's experienced charges will be unfazed by the challenge ahead.

Liverpool have show crucial improvement in recent weeks, but they have consistently struggled against Los Blancos, and Ancelotti will confident of keeping the tie alive ahead of the second leg in Madrid.