Murray State vs. Louisville Predictions, Picks & Odds Week 2: Cardinals Huge Favorites Over Racers

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06 September 2023

Murray State vs. Louisville Predictions, Picks & Odds Week 2: Cardinals Huge Favorites Over Racers

After a thrilling season-opening win, the LouisvilleCardinals host the Murray State Racers in Week 2 as we check out our top MurrayState vs. Louisville prediction based on the best college football odds.

The Louisville Cardinals went to Atlanta and defeated the Georgia Tech Yellow Jackets in aWeek 1 thriller to open the season 1-0. Cardinals quarterback Jack Plummer threw for 247 yards andthree touchdowns while running back Jawhar Jordan ran for 96 yards, including 74 on afourth-quarter touchdown run.

The Murray State Racers experienced no such drama in their Week 1 win over the Presbyterian BlueHose. They outgained the Blue Hose 484 yards to 196 while possessing the ball for almost 37 minutes.Eric Phoenix and DJ Williams each saw meaningful time under center, while five different rushers cracked 25 yards.

Hereis our best Murray State vs. Louisville prediction and college football picks (odds via our best college footballbetting sites; pick confidence based on a 1-to-5-star scale).

Murray State vs. Louisville prediction: Week 2

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Aftera gutsy Week 1 win, the Cardinals basically get a bye week before they take on the Indiana Hoosiers in Week 3. While the Cardinalsmay be a bit hung over after such a dramatic victory, it shouldn’t take long for them to blow this game wide open.

Thehardest part about picking a matchup like this is knowing how long starters stay on the field. It’s unlikely Plummer plays much in thesecond half, and after Jordan ran the ball just seven times in Week 1, it’s difficult to imagine the Cardinals overusing him this week with so many meaningful contests on the horizon.

Withsuch a predicament, back the Under. The Cardinals will be alittle lackadaisical as they take the Racers for granted, but Murray State isn't good enough to take advantage of this lapse and put points on the board early.

Aftera low-scoring first half, the Cardinals should start to pour it on in the second session.But they won’t score so many points that they push this total Over on their own. It’shard to know whether or not they'll score enough to cover the incrediblylarge spread of 41 for our college football Week 2 predictions.

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Murray State vs. Louisville best odds

OnlyDraftKings and FanDuel released totals for this game as of Wednesday evening. Since DraftKings lists the total at 54.5 instead of 54, it's the place to make our Under wager.

Sincethis isn't a must-play by any means, you could wait to see what totals theother best sports betting apps release, then play the highest number. Additionally, if anyof these best sports betting sites release first-quarter totals, it's definitely worthtaking the Under if it's listed at 13.5 or higher.

Murray State vs. Louisville odds

Thelines for this game were released just hours ago, so there hasn't been muchmovement. With a number this large, expect to see bettors back the underdogeven if there's no reason to believe in them. The Cardinals haven't been agreat in recent years, so there's really no reason to trust them as41-point favorites. This number should drop to 39 or 39.5 before kickoff.

Asfor the total, it’s really hard to say what will happen. The number is at 54.5right now, so oddsmakers believe the Racers can score at leasta few points in this one. It’s hard to trust FCS teams against Power 5opponents, so maybe bettors will support the Under. But then again, theCardinals' offense should have a field day. Don’t expecttoo much movement with the total.