NBA picks: Bulls vs. Thunder prediction, odds, over/under, spread, injury report for Wednesday, Nov. 22

The Chicago Bulls (5-10) will travel to take on the Oklahoma City Thunder (10-4) on Wednesday night. This is the second time these teams have faced off this season as the Thunder won the first matchup 124-104 on October 25. Tipoff from Paycom Center is set for 8 p.m. ET.

Dalen Terry (knee) and Lonzo Ball (knee) are the two guys out for the Bulls while Jalen Williams (hip) will be out for the Thunder. That is a big loss for Oklahoma City as he is averaging 17.5 points and four rebounds per game. Alex Caruso, Zach Lavine and Patrick Williams are probable for Chicago.

Oklahoma City is a 7-point favorite at DraftKings Sportsbook and the total sits at 225.5. On the moneyline, the Thunder are -278 while the Bulls are +225.

Bulls vs. Thunder, 8 p.m. ET

Pick ATS: Bulls +7

I am going with the Bulls to cover with Williams out. It has been a dreadful season for the Bulls so far, but they were able to get a big win over the Heat on Saturday. This is the game that they need to win and I expect guys like Lavine and DeMar DeRozan to carry this team to a victory. Shai Gilgeous-Alexander has been one of the best players in the NBA the past two seasons. This should be a close matchup, and I’ll give the edge to Chicago’s veterans to cover this line.

Over/Under: Under 225.5

Unders are 3-2 in Chicago’s road games and 3-4 in Oklahoma City’s home games. The only way the Bulls have a shot in this matchup is to limit the Thunder defensively and slow down the pace on both ends of the court. I expect to see a physical game that wears both teams out on offense. Williams being out will impact the Thunder offensively as well.