NFL Against the Spread Picks Power Rankings: Our Top 10 ATS Bets and Predictions for Week 15

The Detroit Lions have been a powerhouse against the spread for the last six weeks. They have made their seventh consecutive appearance in the NFL power rankings.

Brock Purdy is the best quarterback in the NFL. The San Francisco 49ers are favored to beat the Seattle Seahawks this week. The power rankings of my favorite point-spread picks for Week 15 of the season are as of Monday, Dec. 12 at 12:30 p.m. ET.

The Houston Texans are 17.5-point underdogs against the Kansas City Chiefs. The Chiefs are 13-points favorites over the Texans. The Texans almost beat the Dallas Cowboys on the road in Week 14.

Seahawks are a 9th-ranked power pick in the NFL's power rankings. The 49ers lost at home to the Carolina Panthers. The game is a toss-up between the 49er's and Seahawks' quarterback.

Vikings are 4.5-point favorites over the Colts. The Vikings are 10-3. Jeff Saturday's team is fading under him. The spread will shift to Vikings -4. 5 from Vikings-4 as the week progresses.

The market has finally caught up with the Detroit Lions. Jets are 2-point favorites over the Lions, which is close to the look-ahead line of Jets -2.5.

The Dolphins are trading at the key number of seven points. The Dolphins lost to the San Francisco 49ers and Los Angeles Chargers. Bills are 6.5-point favorites over Dolphins in Week 15. Caesars offers Dolphins at +7. 5 (-110), but Caesar offers the better line at -7 (- 110).

Dallas Cowboys lost to the Texans in Week 14. Jacksonville Jaguars beat the Tennessee Titans a week earlier. Sportsbooks have opened this line a little lower than I hadanticipated. DraftKings has moved the line to Cowboys -5.

Tyler Huntley is the probable starting quarterback for the Cleveland Browns against the Baltimore Ravens. The Browns are 2.5-point favorites at PointsBet, while the Ravens are 3. 5-points favorites. The line of Browns -2.0 (-110 via Pointsbet is more advantageous than the spread available at FanDuel.

The Philadelphia Eagles are 12-point favorites over the Chicago Bears in Week 15. The Eagles beat the New York Giants and the Titans. PointsBet offers the lowest spread and lowest juice on the Eagles at -8.5 and -107. DraftKings is trading the Philadelphia at -9.

Josh McDaniels and the Las Vegas Raiders were defeated by Saturday and by the Colts after taking over the team just a few days before. Baker Mayfield had only 24 hours to learn the Los Angeles Rams' playbook. The market will make the Patriots 2-point favorites against the Arizona Cardinals on Monday Night Football.

Titans are 1-point favorites over the Chargers. The Titans have lost three straight games. Mike Vrabel is a head coach we trust. The Chargers are 2.5-points favorites. At Caesars and BetMGM, Titans +3 trades at -120, while at PointsBet it trades for -107.

NFL against-the-spread picks are made 12/12/2022 at 12:30 p.m. ET.