NFL Week 2 Odds: Point Spreads, Moneylines, & Totals

NFL Week 2 odds are available from around the sports betting marketplace. Los Angeles Chargers and Kansas City Chiefs meet on Thursday night.

The NFL's Week 2 point spreads and odds are via FanDuel as of Monday, Sept. 12.

The Chiefs beat the Arizona Cardinals 44-28 in their first game. The Chiefs are playing against the Chargers. Last year the Chiefs won 30-24 at Arrowhead Stadium.

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Bengals are at Cowboys. Cowboys QB Dak Prescott needs surgery on his thumb and will miss several weeks. Backup QB Cooper Rush completed 7 of 13 passes for 64 yards in relief duty.

Dolphins beat the Ravens 22-10 last season. The line has dropped from Baltimore -4 on Friday to -3.5 as of today.

Jets are underdogs at Browns (-6.5, 40. 5). Jets fans are disappointed with their team's performance every year. Browns have a solid defense and a good offense.

Colts are at home against Jaguars. Jacksonville is favored by 4.5 points.

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Buccaneers are at home against the Saints. The Saints beat Tampa Bay twice last season.

Patriots are coming off another loss to the Dolphins. The Patriots are 2-8 in their last 10 games at Miami. Patriots QB Mac Jones injured his back in the Week 1 game. Steelers defensive stalwart T.J. Watt left the game against Cincinnati with a torn pec. Najee Harris is injured and the Steelers may be without their best player on offense in RB Najees Harris.

Panthers are still reeling from their loss yesterday. The Giants won 25-3 last season.

Commanders are the underdogs at Lions. One bettor at Two Kings Sportsbook in North Carolina would bet the Lions all day.

Matthew Stafford will try to rebound from a poor performance against the Bills. Rams were a double-digit favorite three times last season. They were 1-2 ATS in those games.

Seahawks are playing the 49ers in the NFL's Week 2. The game is a toss-up.

Cardinals are at home against the Raiders. Arizona lost to the Chargers in the first game.

Texans were a surprise in Week 1, taking Indianapolis to overtime and coming out with a hard-fought tie. The Texans are a double-digit road dog at Denver.

The Bears beat the Vikings in the first game of the NFL season. The Packers lost to New Orleans in Week 1 last year.

Green Bay Packers are down by 1 with 37 seconds left on the clock.

Titans are the underdogs at Buffalo (-9.5, 49. 5). The two teams met last October with the Bills laying -6 on the road. The Titans won the game outright, 34-31.

Vikings at Eagles is a game we're bullish on in 2022. Philadelphia is down to +600 at FanDuel as of today. Minnesota was +300 to win the NFC North in early August. The Vikings are now +130.