Ohio State Buckeyes vs. Northwestern Wildcats Odds, Lines, Prediction, and Picks- November 5

The Ohio State Buckeyes are the No. 2 team in the nation. They are going to play the Northwestern Wildcats in Evanston, Indiana. The game follows the Buckeye's victory over Penn State last week.

Ohio State Buckeyes are the favorite to beat Northwestern Wildcats. C.J. Stroud has been outstanding this season with a 29:4 TD-to-interception ratio. TreVeyon Henderson and Miyan Williams are a 1-2 punch at the running back position. Emeka Egbuka and Marvin Harrison Jr. have stepped up in the absence of Jaxon Smith-Njigba. Northwestern has lost seven straight games.

Ohio State Buckeyes host Northwestern Wildcats on November 5th.

Ohio State Buckeyes and Northwestern Wildcats are playing each other on Saturday, November 5 at 12:00 PM ET at Ryan Field in Evanston, Indiana.

Ohio State Buckeyes are favored to beat Northwestern Wildcats. Northwestern hasn't won a game in two months. The over on the Ohio State's passing game is a good bet.

Ohio State Buckeyes should have their 2nd-string playing by the early 2 second half against Northwestern.

Ohio State Buckeyes are -38 (-110) against Northwestern Wildcats.